Abstract Library

#895 Determination of a Prognostic Classification System in Metastatic Grade 1 and 2 Pancreatic Neuroendocrine Tumors (PNETs)

Introduction: There is no clinical prognostic risk stratification tool available for metastatic grade 1 and 2 PNETs, which are a heterogeneous group.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Fernández Plana J, Bestanti C, Thirlwell C, Campana D, Handkiewicz Junak D,

Keywords: classification system, PNETS, neuroendocrine tumors ,

#622 Evaluation of Mucin and Neuroendocrine Expression in Diffuse Gastric Cancer with Signet Ring Cell Morphology

Introduction: A proportion of diffuse gastric carcinoma, according to the Lauren classification system, has signet ring cell morphology. Signet ring cells are characterized by a peripherally placed nucleus and a central amorphous substance, which is reported to be mucin based on Periodic Acid Schiff positivity (PAS). PAS is not a specific staining method for mucin. Neuroendocrine expression has previously been reported in tumor cells in diffuse type gastric cancer.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Sørdal �

Authors: Sørdal �, Qvigstad G, Nordrum I, Waldum H,

Keywords: gastric signet ring cell carcinoma, mucin, neuroendocrine markers, PAS,

#251 Ki-67 is a Better Prognostic Marker than Mitotic Count in Neuroendocrine Tumors

Introduction: The recent classification system proposed by ENETS assigns grade by Ki-67 index +/- mitotic count. It has been adopted into routine practice but there is limited data on the relationship between them.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Khan M, El-Khouly F, Toumpanakis C, Meyer T, Caplin M,

Keywords: survival, neuroendocrine tumor, Ki-67, proliferation, biomarker,

#134 Gastrointestinal neuroendocrine tumors: tumor characteristics and long-term clinical outcome in the German NET registry

Introduction: Prognosis of neuroendocrine tumors (NETs) has been difficult to predict due to heterogenous tumor biology, various classification systems, and lack of reliable and recent data due to the rarity of these tumors.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Maasberg S

Authors: Maasberg S, König A, Rinke A, Anlauf M, Isermann B,

Keywords: gastrointestinal, epidemiology, overall survival, WHO-classification, grading,

#129 Grade according to Ki-67 or mitotic count in gastroenteropancreatic neuroendocrine tumors

Introduction: Gastroenteropancreatic neuroendocrine tumors (NETs) are uncommon tumors with a reported incidence of 2.5-5 per 100000 population. The recent classification system of NETs proposed by the European Neuroendocrine Tumor Society (ENETS) uses both Ki-67 labelling index and mitotic index to assign grade (low, intermediate, high). It has been adopted into routine practice but there is limited data on the relationship between these indices and their effect on classification.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Khan M

Authors: Khan M, Toumpanakis C, Jamieson A, Chilkunda D, Watkin J,

Keywords: neuroendocrine tumor, grade, Ki-67, mitoses ,